吳愛國(guó)
中國(guó)科學(xué)院甯波材料技術與工程研究所研究員，博士生導師，黨委委員，所學(xué)術委員會副主任，先進(jìn)診療材料與技術實驗室主任。江西南昌人，中共黨員。
個人教育與研究經(jīng)曆:
1994-1998年 南昌大學(xué)化學(xué)系 本科 (優秀畢業生)
1998-2003年 中科院長(cháng)春應化所-電分析化學(xué)國(guó)家重點實驗室理學(xué)博士
指導老師 汪爾康院士／李壯研究員（獲中科院彭蔭剛獎學(xué)金）
2004-2005年 德國(guó)馬爾堡大學(xué) 博士後(hòu)（Norbert A Hampp教授課題組）
2005-2006年 美國(guó)加州理工學(xué)院 博士後(hòu)（1999年諾貝爾化學(xué)獎獲得者Ahmed H. Zewail教授課題組）
2006-2009年 美國(guó)西北大學(xué)醫學(xué)院 助理研究員h（Gayle E. Woloschak教授課題組）
2009-2018年 中國(guó)科學(xué)院甯波材料技術與工程研究所 納米事(shì)業部 研究員 (獨立團隊負責人)
2019-至 今 中國(guó)科學(xué)院甯波材料技術與工程研究所 先進(jìn)診療材料與技術實驗室 主任
個人主要榮譽:
國(guó)際生物材料科學(xué)與工程學(xué)會聯合會會士(FBSE),
英國(guó)皇家化學(xué)會會士(FRSC),
英國(guó)皇家生物學(xué)會會士(FRSB),
中國(guó)生物材料學(xué)會理事(shì),
中國(guó)生物材料學(xué)會：影像材料分會常委、科普專業委員會委員、
生物複合材料及醫學(xué)轉化分會常委、生物醫用高分子分會委員、再生醫學(xué)材料分會委員,
中國(guó)生物物理學(xué)會材料生物學(xué)與智能(néng)診療技術分會 副主任委員,
中國(guó)抗癌協會納米腫瘤學(xué)專業委員會 副主任委員,
中國(guó)超聲醫學(xué)工程學(xué)會超聲分子影像專業委員會 副主任委員,
中國(guó)生物醫學(xué)工程學(xué)會納米生物醫學(xué)工程學(xué)分會 副主任委員,
國(guó)化學(xué)會分析化學(xué)學(xué)科委員會委員,
中科院人才 2010年入選，2011年獲擇優支持，
浙江省傑出青年基金 (2011，結題優秀)/省QR計劃（2012），
中國(guó)分析測試學(xué)會科學(xué)技術特等獎(2014，2/10),
甯波市科學(xué)技術獎一等獎(2016，1/7),
美國(guó)西北大學(xué)醫學(xué)院 Adjunct Professor 2013-2016,
德國(guó)馬爾堡大學(xué) 訪問教授 2015.01-2016.01,
中國(guó)科學(xué)院甯波材料技術與工程研究所 所長(cháng)特别獎(首次) 團隊負責人 2017,
Nano Research雜志納米生物科技領域全球Young Innovator Awards獲獎者 2018，
甯波市突出貢獻專家 2019，
國(guó)家自然基金傑出青年基金 2020。
個人學(xué)術業績:
吳愛國(guó)，研究員、國(guó)家級人才、中科院人才，國(guó)際生物材料科學(xué)與工程學(xué)會聯合會會士(FBSE)，英國(guó)皇家生物學(xué)會會士(FRSB)，英國(guó)皇家化學(xué)會會士(FRSC)。現任中科院甯波材料所學(xué)術委員會副主任、中國(guó)生物材料學(xué)會理事(shì)、中國(guó)生物物理學(xué)會材料生物學(xué)與智能(néng)診療技術分會、中國(guó)抗癌協會納米腫瘤學(xué)專業委員會、中國(guó)超聲醫學(xué)工程學(xué)會超聲分子影像專業委員會及中國(guó)生物醫學(xué)工程學(xué)會納米生物醫學(xué)工程學(xué)分會等4個副主任委員及中國(guó)化學(xué)會分析化學(xué)學(xué)科委員會委員等。
專注于分子影像探針生物材料及其相關儀器設備研究，在MRI探針材料、超聲造影成(chéng)像探針材料及NPY靶向(xiàng)的腫瘤治療可視化成(chéng)像探針材料和儀器開(kāi)發(fā)等方面(miàn)形成(chéng)了獨創性的研究體系做出了系統性貢獻，先後(hòu)在Adv Mater、Nano Lett、ACS Nano、Biomaterials及Chem Soc Rev等發(fā)表通訊（含共同）文章300餘篇，被(bèi)引用超2萬次，獲Nano Research雜志首屆全球Nanobiotech青年創新獎(2018)等、中國(guó)分析測試學(xué)會科學(xué)技術獎勵特等獎及甯波市科學(xué)技術一等獎等，出版專著4部（Wiley和中國(guó)科學(xué)出版社等）。獲得中歐美專利112件（含美歐4件），牽頭制定國(guó)家和團體标準各1項。
聯系方式：電話：0574-86685039 E-mail：aiguo@nimte.ac.cn
主要論文
1. Xiawei Xu, Jie Lin*, Yanhong Guo, Xiaoxia Wu, Yanping Xu, Dinghu Zhang, Xiangzhi Zhang, Xie Yujiao, Jing Wang, Chengyang Yao, Junlie Yao, Jie Xing, Yi Cao, Yanying Li, Wenzhi Ren, Tianxiang Chen, Yong Ren*, Aiguo Wu*, TiO2-based Surface-Enhanced Raman Scattering bio-probe for efficient circulating tumor cell detection on microfilter, Biosensors and Bioelectronics,2022,210,114305.
2. Yanying Li, Yuanbo Pan, Yinjie Wang, Zhenqi Jiang, Ozioma U. Akakuru, Mingli Li, Xianyun Zhang, Bo Yuan, Jie Xing, Lijia Luo, Dan Larhammar, Aiguo Wu, Juan Li*, A D-peptide ligand of neuropeptide Y receptor Y1 serves as nanocarrier traversing of the blood brain barrier and targets glioma,Nano Today ,2022,44,101465.
3. Ting Dai#, Wenming He#, Shuangshuang Tu, Jinru Han, Bo Yuan, Chenyang Yao, Wenzhi Ren*, Aiguo Wu*, Black TiO2 nanoprobe-mediated mild phototherapy reduces intracellular lipid levels in atherosclerotic foam cells via cholesterol regulation pathways instead of apoptosis,Bioactive Materials,2022,17,18-28.
4. Yuanbo Pana#, Canxin Xub#, Hongzhang Deng, Qing You, Chenyang Zhao, Yanying Li, Qianqian Gao, Ozioma Udochukwu Akakuru, Juan Li*, Jianmin Zhang*, Aiguo Wu*, Xiaoyuan Chen*, Localized NIR-II laser mediated chemodynamic therapy of glioblastoma,Nano Today,2022,43,101435.
5. Chen Dong#, Mingsheng Xu#, Shuna Wang#, Menghui Ma, Ozioma U. Akakuru, Haizhen Ding, Aiguo Wu*, Zhengbao Zha*, Xuemei Wang, Hong Bi*, Fluorescent carbon dots with excellent moisture retention capability for moisturizing lipstick,Journal of Nanobiotechnology,2021,19,299.
6. Lin Huang#, Jie Feng#, Wenpei Fan*, Wei Tang, Xiaoxiang Rong, Wangjun Liao, Zhenni Wei, Yikai Xu, Aiguo Wu*, Xiaoyuan Chen*, Zheyu Shen*, Intelligent Pore Switch of Hollow Mesoporous Organosilica Nanoparticles for High Contrast Magnetic Resonance Imaging and Tumor-Specific Chemotherapy,Nano Letters,2021,21,9551−9559.
7. Yuanwei Pan, Xuehua Ma, Chuang Liu, Jie Xing, Suqiong Zhou, Badri Parshad, Tanja Schwerdtle,Wenzhong Li*, Aiguo Wu*, Rainer Haag*,Retinoic Acid-Loaded Dendritic Polyglycerol-Conjugated Gold Nanostars for Targeted Photothermal Therapy in Breast Cancer Stem Cells,ACS Nano,2021,15,15069-15084.
8. Chuang Liu, Shan Sun, Qiang Feng, Gongwei Wu, Yiting Wu, Na Kong, Zhangsen Yu, Junlie Yao, Xingcai Zhang, Wei Chen, Zhongmin Tang, Yufen Xiao, Xiangang Huang,Aman Lv, Chenyang Yao, Haibo Cheng, Aiguo Wu*, Tian Xie*, Wei Tao*,Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ß-Elemene for Cancer Therapy,Advanced Materials,2021,33,2102054.
9. Chen Dong, Shuna Wang, Menghui Ma, Peifa Wei, Yan Chen, Aiguo Wu∗, Zhengbao Zha*, Hong Bi*, Inhibition of oxidative stress in vivo through enzyme-like activity of carbon dots,Applied Materials Today,2021,25,101178.
10. Zhenqi Jiang, Xiao Han, Yang Du, Yanying Li, Yong Li, Juan Li*, Jie Tian*, Aiguo Wu*, Mixed Metal Metal−Organic Frameworks Derived Carbon Supporting ZnFe2O4/C for High-Performance Magnetic Particle Imaging,Nano Letters,2021,21,2730-2737.
11. Yuanbo Pan#, Canxin Xu#, Hongzhang Deng, Qing You, Chenyang Zhao, Yanying Li, Qianqian Gao, Ozioma Udochukwu Akakuru, Juan Li*, Jianmin Zhang*, Aiguo Wu*, Xiaoyuan Chen*, Localized NIR-II laser mediated chemodynamic therapy of glioblastoma, Nano Today,2022,43,101435.
12. Zhenqi Jiang#, Yanying Li#, Zhenni Wei, Bo Yuan,Yinjie Wang, Ozioma Udochukwu Akakuru,Yong Li, Juan Li*, Aiguo Wu*,Pressure-induced amorphous zeolitic imidazole frameworks with reduced toxicity and increased tumor accumulation improves therapeutic efficacy In vivo,Bioactive Materials,2021,6,740-748.
13.Chenyang Yao#, Fang Yang# *, Li Sun#, Yuanyuan Ma, Stefan G. Stanciu, Zihou Li, Chuang Liu, Ozioma Udochukwu Akakuru, Lipeng Xu, Norbert Hampp, Huanming Lu, Aiguo Wu*, Magnetically switchable mechano-chemotherapy for enhancing the death of tumour cells by overcoming drug-resistance,Nano Today,2020,35,100967.
14. Zhenqi Jiang, Bo Yuan, Yinjie Wang, Zhenni Wei, Shan Sun, Ozioma Udochukwu Akakuru, Yong Li, Juan Li∗, Aiguo Wu*, Near-infrared heptamethine cyanine dye-based nanoscale coordination polymers with intrinsic nucleus-targeting for low temperature photothermal therapy,Nano Today,2020,34,100910.
15. Shan Sun, Qiao Chen, Zhongdi Tang, Chuang Liu, Zhongjun Li, Aiguo Wu, Hengwei Lin*, Tumor Microenvironment Stimuli-Responsive Carbon Dots-Cu2+ Nanoassmeblies for Synergistic Cancer Therapy,Angew Chem Int Ed,2020,59,1041–21048.
16. Chuang Liu#, Junlie Yao#, Jiapeng Hu, Ozioma Udochukwu Akakuru#, Shan Sun, Tianxiang Chen*, Aiquo Wu*, Navigating nmof-mediated enzymatic reactionsfor catalytic tumor-specific therapy,Materials Horizons,2020,7,3176-3186.
17. Ozioma Udochukwu Akakuru, Chuang Liu, M. Zubair Iqbal*, Gohar Ijaz Dar, Gao Yang, Kun Qian, Elvis Ikechukwu Nosike, Jie Xing, Zhoujing Zhang, Yanying Li, Juan Li*, Aiguo Wu*, A hybrid organo-nanotheranostic platform of superlative biocompatibility for near-infrared-triggered fluorescence imaging and synergistically enhanced ablation of tumor, Small,2020,16,2002445.
18. Zhenni Wei, Zhenqi Jiang, Chunshu Pan, Jianbi Xia, Kaiwei Xu, Ting Xue, Bo Yuan, Ozioma Udochukwu Akakuru, Chengjie Zhu,Guilong Zhang, Zheng Mao, Xiaozhong Qiu *, Aiguo Wu*, Zheyu Shen *,Ten-Gram-Scale Facile Synthesis of Organogadolinium Complex Nanoparticles for Tumor Diagnosis,Small,2020,16,1906870.
19. Zheyu Shen, Ting Liu, Zhen Yang, Zijian Zhou, Wei Tang, Wenpei Fan*, Yijing Liu, Jing Mu, Ling Li, Vladimir I Bregadze, Swadhin K Mandal, Anna A Druzina, Zhenni Wei, Xiaozhong Qiu*, Aiguo Wu*, Xiaoyuan Chen*, Small-sized gadolinium oxidebased nanoparticles for high-efficiency theranostics of orthotopic glioblastoma, Biomaterials,2020,235,119783.
20. Xiaoyuan Zhang#, Coucong Gong#, Ozioma Udochukwu Akakuru, Zhiqiang Su*, Aiguo Wu*, The design and biomedical applications of self-assembled two-dimensional organic biomaterials,Chem Soc Rev,2019,48,5564-5595.
21. Jiang Zhenqi#, Yuan Bo#, Qiu Nianxiang, Wang Yinjie, Sun Li, Li Yanyin, Li Yong, Du Shiyu, Li Juan, Wu Aiguo*, Manganese-Zeolitic Imidazolate Frameworks-90 with High Blood Circulation Stability for MRI-Guided Tumor Therapy,Nano-Micro Letters,2019,11,61.
20. Zheyu Shen, Wenpei Fan*, Zhen Yang, Yijing Liu, Vladimir I. Bregadze, Swadhin K. Mandal, Bryant C. Yung, Lisen Lin, Ting Liu*, Wei Tang, Lingling Shan, Yuan Liu, Shoujun Zhu, Sheng Wang, Weijing Yang, L. Henry Bryant, Duong T. Nguyen, Aiguo Wu*, Xiaoyuan Chen*, Exceedingly Small Gadolinium Oxide Nanoparticles with Remarkable Relaxivities for Magnetic Resonance Imaging of Tumors, Small,2019,15,1903422.
21. Chuang Liu, Jie Xing, Ozioma Udochukwu Akakuru, Lijia Luo, Shan Sun, Ruifen Zou, Zhangsen Yu, Qianlan Fang, Aiguo Wu*, Nanozymes-Engineered Metal-Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy,Nano Letters,2019,19,5674-5682.
22. Lijia Luo, Muhammad Zubair Iqbal, Chuang Liu, Jie Xing, Ozioma Udochukwu Akakurua, Qianlan Fanga, Zihou Li, Yunlu Dai, Aiguo Li, Yong Guan, Aiguo Wu*, Engineered nano-immunopotentiators efficiently promote cancer immunotherapy for inhibiting and preventing lung metastasis of melanoma, Biomaterials,2019,223,119464.
23. Zhenqi Jiang#, Yinjie Wang#, Li Sun, Bo Yuan, Yuchen Tian, Lingchao Xiang,Yanying Li, Yong Li, Juan Li∗, Aiguo Wu*,Dual ATP and pH responsive ZIF-90 nanosystem with favorable biocompatibility and facile post-modification improves therapeutic outcomes of triple negative breast cancer in vivo,Biomaterials,2019,197,41-50.
24. Zheyu Shen, Jibin Song, Zijian Zhou, Bryant C. Yung, Maria A. Aronova, Yan Li, Yunlu Dai, Wenpei Fan, Yijing Liu*, Zihou Li, Huimin Ruan, Richard D. Leapman, Lisen Lin, Gang Niu, Xiaoytianuan Chen*, Aiguo Wu*, Dotted Core-Shell Nanoparticles with Superhigh r1 and Very Low r2/r1 for T1-Weighted MRI of Tumors,Adv Mater,2018,30,1803163.
25. Zheyu Shen, Jibin Song, Bryant C. Yung, Zijian Zhou*, Aiguo Wu*, Xiaoyuan Chen*, Emerging Strategies of Cancer Therapy Based on Ferroptosis, Adv Mater,2018,30,1704007.
26. Qiuyu Gong#, Ruifen Zou#, Jie Xing, Lingchao Xiang, Renshuai Zhang, Aiguo Wu*, A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine,Advanced Science,2018,5,1700664.
27. Zheyu Shen,Ting Liu, Yan Li, Joseph Lau, Zhen Yang, Wenpei Fan, Zijian Zhou, Changrong Shi, Chaomin Ke, Vladimir I. Bregadze,Swadhin K. Mandal, Yijing Liu*,Zihou Li, Ting Xue, Guizhi Zhu, Jeeva Munasinghe, Gang Niu, Aiguo Wu*, Xiaoyuan Chen*,Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors,ACS Nano,2018,12,11355-11365.
28. Chuang Liu, Lijia Luo, Leyong Zeng, Jie Xing, Yuanzhi Xia, Shan Sun, Luyun Zhang, ZheYu, Junlie Yao, Zhangsen Yu,Ozioma Udochukwu, Akakuru, Madiha Saeed, Aiguo Wu*,Porous gold nanoshells on functional NH2-MOFs: facile synthesis and designable platforms for cancer multiple therapy,Small,2018,14,1801851.
29. Yuanzhi Xia#, Xuehua Ma #, Junhua Gao, Guoxin Chen, Zihou Li, Xiaoxia Wu, Zhangsen Yu, Jie Xing, Li Sun, Huimin Ruan, Lijia Luo，Lingchao Xiang, Chen Dong, Wenzhi Ren, Zheyu Shen *, Aiguo Wu*, A Flexible Caterpillar-Like Gold Nanoparticle Assemblies with Ultra-Small Nanogaps for Enhanced Dual-Modal Imaging and Photothermal Therapy, Small,2018,14,1800094.
30. Zhenqi Jiang#, Yuchen Tian#, Dingying Shan, Yinjie Wang, Ethan Gerhard, Jianbi Xia, Rong Huang, Yan He, Aiguo Li, Jianchao Tang,Huimin Ruan, Yong Li, Juan Li*, Jian Yang, Aiguo Wu*,pH protective Y1 receptor ligand functionalized antiphagocytosis BPLP-WPU micelles for enhanced tumor imaging and therapy with prolonged survival time,Biomaterials,2018,170,70-81.
31. Bushra Tehseen, Asma Rehman*, Muniba Rahmat, Haq Nawaz Bhatti, Aiguo Wu, Faheem K. Butt, Gul Naz, Waheed S. Khan*, Sadia Z. Bajwa*, Solution growth of 3D MnO2 mesh comprising 1D nanofibres as a novel sensor for selective and sensitive detection of biomolecules, Biosensors and Bioelectronics,2018,117,852-859.
32. Zheyu Shen, Aiguo Wu*, Xiaoyuan Chen*, Current detection technologies for circulatingtumor cells,Chem Soc Rev,2017,46,2038-2056.
33. Zheyu Shen#, Tianxiang Chen#, Xuehua Ma, Wenzhi Ren, Zijian Zhou, Guizhi Zhu, Ariel Zhang, Yijing Liu, Jibin Song*, Zihou Li, Huimin Ruan, Wenpei Fan, Lisen Lin, Jeeva Munasinghe, Xiaoyuan Chen*, Aiguo Wu*, Multifunctional Theranostic Nanoparticles Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for T 1 ‑Weighted Magnetic Resonance Imaging and Chemotherapy,ACS Nano,2017,11,10992-11004.
34. Juan Li#, Yuchen Tian#, Dingying Shan, An Gong, Leyong Zeng, Wenzhi Ren, Lingchao Xiang, Ethan Gerhard, Jinshun Zhao, Jian Yang, Aiguo Wu*, Neuropeptide Y Y1 receptor-mediated biodegradable photoluminescent nanobubbles as ultrasound contrast agents fortargeted breast cancer imaging, Biomaterials,2017,116,106-117.
35. Leyong Zeng, Yuanwei Pan, Ruifen Zou, Jinchao Zhang, Ying Tian, Zhaogang Teng, Shouju Wang, Wenzhi Ren, Xueshan Xiao, Jichao Zhang, Lili Zhang, Aiguo Li, Guangming Lu*, Aiguo Wu*,808 nm-excited upconversion nanoprobes with low heating effect fortargeted magnetic resonance imaging and high-efficacyphotodynamic therapy in HER2-overexpressed breast cancer, Biomaterials,2016,103,116-127.
36. Lulu Pan, Shan Sun, Aidi Zhang, Kai Jiang, Ling Zhang, Chaoqing Dong, Qing Huang, Aiguo Wu*, Hengwei Lin*, Truly fluorescent excitation-dependent carbon dots and their applications in multicolor cellular imaging and multidimensional sensing,Adv Mater,2015,27,7782–7787.
37. Kai Jiang,Shan Sun, Ling Zhang, Yue Lu, Aiguo Wu*, Congzhong Cai, Hengwei Lin*,Red Green and Blue Luminescence by Carbon Dots: Full-Color Emission Tuning and Multicolor Cellular Imaging,Angew Chem Int Ed,2015,127(18),5450-5453.
38. Zheyu Shen, Hao Wu, Sugeun Yang, Xuehua Ma, Zihou Li, Mingqian Tan*, Aiguo Wu*, A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by noncancerouscells, Biomaterials,2015,70,1-11.
39. Leyong Zeng, Yuanwei Pan, Ying Tian, Xin Wang, Wenzhi Ren, Shouju Wang, Guangming Lu*, Aiguo Wu*, Doxorubicin-loaded NaYF4: Yb/Tm-TiO2 inorganic photosensitizers for NIR-triggered photodynamic therapy and enhanced chemotherapy in drug-resistant breast cancers, Biomaterials,2015,57,93-106.
40. Ling'e Zhang, Leyong Zeng*, Yuanwei Pan, Song Luo, Wenzhi Ren, An Gong, Xuehua Ma, Hongze Liang, Guangming Lu*, Aiguo Wu*, Inorganic photosensitizer coupled Gd-based upconversionluminescent nanocomposites for in vivo magnetic resonance imagingand near-infrared-responsive photodynamic therapy in cancers, Biomaterials,2015,44,82-90.
41. Xuefeng Yan, Gang Niu, Jing Lin, Albert J. Jin, Hao Hu, Yuxia Tang, Yujie Zhang, Aiguo Wu*, Jie Lu, Shaoliang Zhang, Peng Huang*, Baozhong Shen*, Xiaoyuan Chen*, Enhanced fluorescence imaging guided photodynamic therapy ofsinoporphyrin sodium loaded graphene oxide, Biomaterials,2015,42,4294-4302.
42. Zhenzhi Shi, Wenzhi Ren, An Gong, Xinmei Zhao, Yuehong Zou,Eric Michael Bratsolias Brown, Xiaoyuan Chen, Aiguo Wu*,Stability enhanced polyelectrolyte-coated gold nanorod-photosensitizer complexes for high/low power density photodynamic therapy,Biomaterials,2014,35,7058-7067.
43. Christine A. Falaschetti, Tatjana Paunesku, Jasmina Kurepa, Dhaval Nanavati, Stanley S. Chou, Mrinmoy De, MinHa Song, Jung-tak Jang, Aiguo Wu*, Vinayak P. Dravid, Jinwoo Cheon, Jan Smalle, Gayle E. Woloschak*, Negatively Charged Metal Oxide Nanoparticles Interact with the 20S Proteasome and Differentially Modulate Its Biologic Functional Effects,ACS Nano,2013,7(9),7759-7772.
44. Kenneth T. Thurn, Tatjana Paunesku, Aiguo Wu*, Eric M. B. Brown, Barry Lai, Stefan Vogt, Jörg Maser, Mohammed Aslam, Vinayak Dravid, Raymond Bergan, Gayle E. Woloschak,Labeling TiO2 Nanoparticles with Dyes for Optical Fluorescence Microscopy and Determination of TiO2-DNA Nanoconjugate Stability,Small,2009,5(11),1318-1325.
申請專利：
(1) 納米材料或微納器件的顯微重複定位方法。
發(fā)明人：吳愛國(guó)，曾樂勇。專利号：ZL200910152441.2
(2）利用ⅤA族或ⅥA族元素化合物檢測金屬陽離子的方法。
發(fā)明人：張付強，吳愛國(guó)，曾樂勇，崔平。專利号：ZL201010251278.8
(3) 一種(zhǒng)Cd2+的檢測方法。
發(fā)明人：吳愛國(guó)，苗利靜，沈折玉，曾樂勇。專利号：ZL201210391120.X
(4) 一種(zhǒng)核殼結構的複合納米材料及其制法和應用。
發(fā)明人：曾樂勇，吳愛國(guó)。專利号：ZL201510405522.4
(5) 一種(zhǒng)核磁共振快速檢測金屬離子與小分子化合物的方法。
發(fā)明人：吳愛國(guó)，陳甯怡，張玉傑。專利号：ZL201510107195.4
(6) 一種(zhǒng)铋基複合納米材料及其腫瘤診斷與治療應用。
發(fā)明人：吳愛國(guó)，史振志，徐裕。專利号：ZL201410788424.9
(7) 一種(zhǒng)新型造影材料、其制備方法及應用。
發(fā)明人：陳天翔，吳愛國(guó)。專利号：ZL201410430551.1
(8) 金屬離子的檢測方法。
發(fā)明人：張付強，吳愛國(guó)，曾樂勇。專利号：ZL201010194041.0
(9) 納米粒子和納米粒子溶膠的制備方法及兩(liǎng)者在磁共振成(chéng)像造影劑中的應用。
發(fā)明人：吳愛國(guó)，曾樂勇，崔平。專利号：ZL201010175917.7
(10) 一種(zhǒng)高産率合成(chéng)（200）晶面(miàn)爲主的納米金棒的制備方法及應用。
發(fā)明人：冷玉敏，吳愛國(guó)，尹訓君。專利号：ZL201110363934.8
(11) 一種(zhǒng)鉛離子的檢測方法。
發(fā)明人：張玉傑，吳愛國(guó)。專利号：ZL201110299385.2
(12) Fe3O4複合TiO2納米粒子及其制備方法以及在磁共振成(chéng)像造影劑中的應用。
發(fā)明人：吳愛國(guó)，曾樂勇。專利号：ZL201010039632.0
(13) 一種(zhǒng)制備不同形貌的銀納米粒子的綠色方法。
發(fā)明人：辛軍委，吳愛國(guó)。專利号：ZL201110378232.7
(14) 水溶性具有核殼結構或核冕殼結構的材料的制備方法。
發(fā)明人：吳愛國(guó)，曾樂勇，張付強，崔平。專利号：ZL201110000844.2
(15) multifunction nanoconjugates for imaging applications and targeted treatment。
發(fā)明人：Ai Guo Wu，Tatjana Paunesku，Gayle E.Woloschak。專利号：US8557290B2
(16) 順磁-上轉換發(fā)光複合納米粒子及其制備方法和應用。
發(fā)明人：曾樂勇，吳愛國(guó)，崔平。專利号：ZL201110032000.6
(17) 一種(zhǒng)水溶性納米複合材料及其制備方法和應用。
發(fā)明人：張穎鑫，吳愛國(guó)，聶秀青。專利号：ZL201110241124.5
(18) 一種(zhǒng)六價鉻離子的檢測方法。
發(fā)明人：辛軍委，吳愛國(guó)。專利号：ZL201110378260.9
(19) 主動靶向(xiàng)型小幹擾核糖核酸輸送載體及其制備方法。
發(fā)明人：沈折玉，吳愛國(guó)，任文智，馬雪華。專利号：ZL201210475752.4
(20) 一種(zhǒng)用于無機光動力治療的複合納米粒子及其制備方法。
發(fā)明人：曾樂勇，吳愛國(guó)。專利号：ZL201210172056.6
(21) 用于檢測和吸附汞離子的雙功能(néng)材料及其合成(chéng)方法和應用。
發(fā)明人：吳愛國(guó)，汪竹青，趙新梅。專利号：ZL201210396580.1
(22) 腫瘤早期診斷用隐形造影材料及其制備方法。
發(fā)明人：沈折玉，吳愛國(guó)。專利号：ZL201210230833.8
(23) 一種(zhǒng)快速檢測溶液中銅離子的方法。
發(fā)明人：吳愛國(guó)，苗利靜，辛軍委。專利号：ZL201210097477.7
(24) Gd2O3-TiO2複合納米粒子及其制備方法和應用。
發(fā)明人：吳愛國(guó)，馬雪華，沈折玉。專利号：ZL201210539796.9
(25) 一種(zhǒng)快速檢測多種(zhǒng)單一金屬離子的檢測試劑及其制備和應用。
發(fā)明人：吳愛國(guó)，冷玉敏。專利号：ZL201210159826.3
(26) 檢測二價汞離子的檢測組合物、方法與試劑盒。
發(fā)明人：吳愛國(guó)，高月霞，沈折玉。專利号：ZL201310091158.X
(27) 一種(zhǒng)檢測二價錳離子的方法。
發(fā)明人：吳愛國(guó)，高月霞，沈折玉。專利号：ZL201210310138.2
(28) 一種(zhǒng)基于納米粒子的腫瘤細胞主動靶向(xiàng)給藥體系及其構建方法。
發(fā)明人：任文智，吳愛國(guó)。專利号：ZL201110397312.7
(29) 一種(zhǒng)檢測二價鎳離子的方法。
發(fā)明人：吳愛國(guó)，楊甯甯，沈折玉。專利号：ZL201210341510.6
(30) 便攜式食品安全檢測試劑及其制備方法與應用。
發(fā)明人：吳愛國(guó)，冷玉敏，張玉傑。專利号：ZL201310511426.9
(31) 基于苯酚類有機分子爲碳源的磁性MFe2O4/C/AOX的複合材料及其制備方法。
發(fā)明人：趙新梅，吳愛國(guó)。專利号：ZL201110334606.5
(32) 靶向(xiàng)型診療聯用藥物及其制備方法和應用。
發(fā)明人：沈折玉，吳愛國(guó)，馬雪華，龔安，任文智，李娟。專利号：ZL201310318107.6
(33) 一種(zhǒng)納米金溶液及利用該納米金溶液檢測Co2+的方法。
發(fā)明人：冷玉敏，吳愛國(guó)。專利号：ZL201110363954.5
(34) 一種(zhǒng)超聲/熒光雙模态微膠囊造影劑的制備方法。
發(fā)明人：吳愛國(guó)，龔安，沈折玉，馬雪華，項靈超。專利号：ZL201310755481.2
(35) 一種(zhǒng)基于苯胺類有機小分子爲碳源的磁性MFe2O4/C/M′的制備方法 。
發(fā)明人：張穎鑫，吳愛國(guó)。專利号：ZL201110334595.0
(36) 一種(zhǒng)半胱氨酸的檢測試劑及檢測方法。
發(fā)明人：吳愛國(guó)，李永龍，沈折玉。專利号：ZL201310367104.1
(37) 一種(zhǒng)腫瘤治療複合納米材料及其制備。
發(fā)明人：任文智，吳愛國(guó)。專利号：ZL201410175018.5
(38) 一種(zhǒng)造影材料、其制備方法及應用。
發(fā)明人：陳天翔，吳愛國(guó)，龔安。專利号：ZL201510465373.0
(39) 三元納米複合藥物、其制備方法和其用于制備治療腫瘤的藥學(xué)組合物的用途。
發(fā)明人：任文智，吳愛國(guó)，曾樂勇，沈折玉，馬雪華。專利号：ZL201310103775.7
(40) 主動靶向(xiàng)型抗腫瘤藥物及其制備方法。
發(fā)明人：李娟，吳愛國(guó)。專利号：ZL201310407938.0
(41) 一種(zhǒng)三價鋁離子檢測試劑及檢測方法。
發(fā)明人：吳愛國(guó)，楊甯甯，高月霞，張玉傑，沈折玉。專利号：ZL201310386230.1
(42) 一種(zhǒng)樣(yàng)品輸入/輸出的聯動裝置 。
發(fā)明人：楊方，吳愛國(guó)，馬園園。專利号：ZL201720764846.1
(43) 主動靶向(xiàng)型抗腫瘤藥物及其制備方法。
發(fā)明人：李娟，吳愛國(guó)。專利号：CH710313B1
(44) 一種(zhǒng)二價汞離子的檢測試劑組合及檢測方法。
發(fā)明人：吳愛國(guó)，李永龍，沈折玉。專利号：ZL201310382118.0
(45) 一種(zhǒng)钼摻雜的納米二氧化钛光催化劑的制備方法。
發(fā)明人：諸葛飛，李振超，吳愛國(guó)，曾樂勇，沈折玉，徐裕，梁淩燕，曹鴻濤。專利号：ZL201510468562.3
(46) 一種(zhǒng)可見光響應的碳摻雜納米二氧化钛催化劑的制備方法。
發(fā)明人：諸葛飛，蔔彥強，李振超，梁淩燕，曹鴻濤，吳愛國(guó)，曾樂勇，沈折玉，徐裕。專利号：ZL201510771557.X
(47) 一種(zhǒng)土壤重金屬固定劑及其制備方法和應用。
發(fā)明人：吳愛國(guó)，劉弘禹，張玉傑。專利号：ZL201510511727.0
(48) 一種(zhǒng)基于表面(miàn)增強拉曼散射技術的複合材料及其制備方法。
發(fā)明人：沈折玉，吳愛國(guó)，武小俠，張玉傑，阮慧敏。專利号：ZL201610234754.2
(49) 主動靶向(xiàng)型抗腦腫瘤藥物及其制備方法。
發(fā)明人：李娟，吳愛國(guó)，田宇辰。專利号：ZL201510535764.5
(50) 軟鏡保護套及其可視軟鏡。
發(fā)明人：漆勇，吳愛國(guó)，李娟，項靈超，蔣振奇。專利号：ZL201820551661.7
(51) 一種(zhǒng)具有Janus 結構的複合納米粒子及其制備方法和應用。
發(fā)明人：Muhammad Zubair Iqbal，吳愛國(guó)，曾樂勇，馬雪華，陳天翔。專利号：ZL201510504659.5
(52) 一種(zhǒng)磁性納米粒子及其制備方法和應用。
發(fā)明人：吳愛國(guó)，陳天翔，馬雪華，鄒瑞芬，Muhammad Zubair Iqbal，項靈超。專利号：ZL201511005964.6
(53) 一種(zhǒng)親水性實心球形材料、制備方法及其應用。
發(fā)明人：楊方，吳愛國(guó)，孫莉。專利号：ZL201710447334.7
(54) 一種(zhǒng)檢測分析儀。
發(fā)明人：楊方，吳愛國(guó)，馬園園。專利号：ZL201710508203.5
(55) 化合物、其制備方法及含有其的熒光探針和應用。
發(fā)明人：吳愛國(guó)，邢潔，龔秋雨，鄒瑞芬。專利号：ZL201711170016.7
(56) 一種(zhǒng)化合物、其制備方法及作爲熒光探針的應用。
發(fā)明人：吳愛國(guó)，鄒瑞芬，龔秋雨。專利号：ZL201711208547.0
(57) 一種(zhǒng)納米生物醫用材料的生産系統及其生産方法。
發(fā)明人：王愛芳，李全，谷新春，王宇光，張志，郭仁君，吳卓娅，林建英，吳愛國(guó)，陳天翔，馬雪華，任文智，李升大，孟啓貴，衛維劍，李子英。專利号：ZL201811365454.3
(58) 一種(zhǒng)納米生物醫用材料的生産系統及其生産工藝。
發(fā)明人：王愛芳，李全，谷新春，王宇光，張志，郭仁君，吳卓娅，林建英，吳愛國(guó)，陳天翔，馬雪華，任文智，李升大，孟啓貴，衛維劍，李子英。專利号：ZL201811365459.6
(59) 一種(zhǒng)基于智能(néng)手機快速現場檢測金屬離子的方法。
發(fā)明人：吳愛國(guó)，董晨，沈折玉。專利号：ZL201510508573.X
(60) 一種(zhǒng)抗癌藥物複合物及其制備方法和應用。
發(fā)明人：李娟，蔣振奇，吳愛國(guó)，王胤傑，袁博，房倩蘭，李彥瑩。專利号：ZL201711209793.8
(61) 一種(zhǒng)主動靶向(xiàng)型超聲/熒光雙模态造影劑及其制備方法和應用。
發(fā)明人：李娟，田宇辰，吳愛國(guó)。專利号：ZL201610235965.8
(62) 一種(zhǒng)納米複合材料、其制備方法及應用。
發(fā)明人：吳愛國(guó)，葉羽凡，邢潔。專利号：ZL201710145917.4
(63) 一種(zhǒng)七甲川硝基吲哚花菁染料以及該染料的制備方法和用途。
發(fā)明人：吳愛國(guó)，蔣振奇，袁博，李娟。專利号：ZL201910175647.0
(64) 一種(zhǒng)用于可代替用力肺活量檢查上機前宣教的峰流裝置。
發(fā)明人：倪霞，郎如意，李娟，吳愛國(guó)，項靈超。專利号：ZL202023063413.4
(65) 沸石咪唑框架結構材料的制備方法。
發(fā)明人：吳愛國(guó)，蔣振奇，李娟，王胤傑，袁博，項靈超，李彥瑩。專利号：ZL201810007681.2
(66) 一種(zhǒng)納米複合材料、其制備方法及應用。
發(fā)明人：張濤，吳愛國(guó)，任文智，蔣振奇，薛婷，馬雪華。專利号：ZL201810907829.8
(67) 一種(zhǒng)新型土壤重金屬固定劑及其制備方法和應用。
發(fā)明人：吳愛國(guó)，劉弘禹，張玉傑。專利号：ZL201610176022.2
(68) 一種(zhǒng)碘離子吸附劑、其制備方法及應用。
發(fā)明人：吳愛國(guó)，孫犁，張玉傑，劉海甯，葉秀深，張慧芳，吳志堅。專利号：ZL201710155686.5
(69) 一種(zhǒng)上轉換熒光數字全息成(chéng)像系統及數字全息成(chéng)像方法。
發(fā)明人：吳愛國(guó)，俞樟森，楊方。專利号：ZL201711173737.3
(70) 一種(zhǒng)二維納米複合材料、其制備方法及其應用。
發(fā)明人：吳愛國(guó)，陳天翔，房倩蘭。專利号：ZL201911411094.0
(71) 一種(zhǒng)複合納米材料、其制備方法及其應用。
發(fā)明人：陳天翔，吳愛國(guó)，馬雪華，任文智。專利号：ZL201810468692.0
(72) 一種(zhǒng)磁性複合納米材料及其制備方法與應用。
發(fā)明人：沈折玉，錢昆，吳愛國(guó)。專利号：ZL202010160598.6
(73) 一種(zhǒng)七甲川吲哚花菁染料的制備方法以及該染料的用途。
發(fā)明人：李娟，袁博，蔣振奇，吳愛國(guó)。專利号：ZL201910176083.2
出版專著：
1. Mingqian Tan*, Aiguo Wu*. “Nanomaterials for Tumor Targeting Theranostics”. World Scientific Publishing, Singapore. 2015. (ISBN: 978-981-4635-41-7).
2. Leyong Zeng, Zheyu Shen, Aiguo Wu*. Chapter 3: Magnetic Nanoparticles for Tumor Targeting Theranostics, pp53-80, Editors: Mingqian Tan*, Aiguo Wu*. “Nanomaterials for Tumor Targeting Theranostics”. World Scientific Publishing, Singapore. 2015. (ISBN: 978-981-4635-41-7).
3. Zhenzhi Shi, Yu Xu, Aiguo Wu* “Chapter III: Gold Nanorods for Biomedical Imaging and Therapy in Cancer”. pp 103-136, Editor: Zhifei Dai, Advances in Nanotheranostics I: Design and Fabrication of Theranostic Nanoparticles. Springer, 2016 (ISSN:2195-0644, ISSN2195-0652 (electronic)).
4. Muhammad Zubair Iqbal, Aiguo Wu* “Chapter V: Magnetic Nanohybrids for Magnetic Resonance Imaging and Phototherapy Applications”, pp101-150, Editor: Donglu Shi, Tissue Engineering and Nanotheranostics, World Scientific Publishing, Singapore. 2017.
5. 吳愛國(guó)，張玉傑。功能(néng)化材料及其環境應用，2019年4月出版，科學(xué)出版社，ISBN978-7-03-060222-0
6. M. Zubair Iqbal, Gohar Ijaz Dar, Israt Ali, and Aiguo Wu*. “Chapter 10: Magnetic
7. Nanomedicine.” pp 269-302, Editor: Xue Xue, Nanomedicine in Brain Diseases. Springer, Germany, 2019. (ISBN 978-981-13-8730-2, ISBN 978-981-13-8731-9 (eBook) )
8. Fang Yang*, Yuanyuan Ma, Stefan G. Stanciu, Aiguo Wu. “chapter-2: Transduction Process-Based Classification of Biosensors.” Editor: 9. Aiguo Wu*, Waheed S. Khan. Nanobiosensors：From Design to Applications. WILEY-VCH, Germany, 2020. (ISBN: 9783527345106)
9. Aiguo Wu, Wenzhi Ren. “TiO2 Nanoparticles: Applications in Nanobiotechnology and Nanomedicine”. WILEY-VCH, Germany, 2020. (ISBN：9783527347247)
10.Aiguo Wu, Waheed S. Khan. “Nanobiosensors：From Design to Applications”. WILEY-VCH, Germany, 2020. (ISBN: 9783527345106)
11. Li Sun, Aiguo Wu, Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications “Chapter 12: Nanofiber-based hydrogels and aerogels”. pp259-278, Editor: Gang Wei, Sangamesh G. Kumbar., Elsevier, Netherlands, 2020. (ISBN 978-0-08-102850-6/ 978-0-08-102851-3)
12. Jie Lin, Aiguo Wu, “Chapter 7: SERS methods based on nanomaterials as a diagnositic tool of cancer”. pp189-212, Editor: Suvardhan Kanchi, Deepali Sharma. Nanomaterials in Diagnostic Tools and Devices, Elsevier, Netherlands, 2020. (ISBN: 978-0-12-817923-9)
13. Elvis Ikechukwu Nosike, Yujie Zhang, Aiguo Wu, “Chapter 22: Magnetic hybrid nanoparticles for environmental remediation”. Pp591-616, Editor: Andrea Ehrmann, Tuan Anh Nguyen, Mazaher Ahmadi, Ali Farmani, Phuong Nguyen-Tri, Magnetic Nanoparticle-Based Hybrid Materials, Elsevier, Netherlands, 2021. (ISBN: 9780128236888/ 9780128236895)